Reviewing Mateon Therapeutics (MATN) and The Competition

Mateon Therapeutics (NASDAQ: MATN) is one of 93 publicly-traded companies in the “Biotechnology” industry, but how does it contrast to its rivals? We will compare Mateon Therapeutics to related companies based on the strength of its institutional ownership, dividends, earnings, analyst recommendations, profitability, risk and valuation.

Volatility and Risk

Mateon Therapeutics has a beta of 1.53, suggesting that its share price is 53% more volatile than the S&P 500. Comparatively, Mateon Therapeutics’ rivals have a beta of 1.14, suggesting that their average share price is 14% more volatile than the S&P 500.


This table compares Mateon Therapeutics and its rivals’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Mateon Therapeutics N/A -224.38% -186.53%
Mateon Therapeutics Competitors -917.30% -187.05% -24.43%

Insider and Institutional Ownership

8.6% of Mateon Therapeutics shares are owned by institutional investors. Comparatively, 20.4% of shares of all “Biotechnology” companies are owned by institutional investors. 2.3% of Mateon Therapeutics shares are owned by insiders. Comparatively, 20.1% of shares of all “Biotechnology” companies are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Earnings & Valuation

This table compares Mateon Therapeutics and its rivals gross revenue, earnings per share and valuation.

Gross Revenue EBITDA Price/Earnings Ratio
Mateon Therapeutics N/A -$14.59 million -0.87
Mateon Therapeutics Competitors $223.74 million $57.84 million -0.73

Mateon Therapeutics’ rivals have higher revenue and earnings than Mateon Therapeutics. Mateon Therapeutics is trading at a lower price-to-earnings ratio than its rivals, indicating that it is currently more affordable than other companies in its industry.

Analyst Ratings

This is a summary of recent ratings and recommmendations for Mateon Therapeutics and its rivals, as reported by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mateon Therapeutics 0 1 3 0 2.75
Mateon Therapeutics Competitors 164 544 1200 16 2.56

Mateon Therapeutics currently has a consensus target price of $2.00, suggesting a potential upside of 325.79%. As a group, “Biotechnology” companies have a potential upside of 53.04%. Given Mateon Therapeutics’ stronger consensus rating and higher possible upside, equities research analysts plainly believe Mateon Therapeutics is more favorable than its rivals.


Mateon Therapeutics rivals beat Mateon Therapeutics on 7 of the 12 factors compared.

About Mateon Therapeutics

Mateon Therapeutics, Inc., formerly OXiGENE, Inc., is a biopharmaceutical company. The Company is focused on the development of vascular disrupting agents (VDAs) for the treatment of cancer. The Company is engaged in developing two clinical stage investigational drugs: VDAs-CA4P and OXi4503. Its lead compound is CA4P, which is also known as combretastatin A4-phosphate, fosbretabulin tromethamine, fosbretabulin and ZYBRESTAT. VDAs selectively targets the vasculature of cancer tumors and obstructs a tumor’s blood supply without disrupting the blood supply to normal tissues. VDAs are in a class of drugs called vascular targeted therapies (VTTs), which also includes anti-angiogenic agents (AAs). CA4P is a reversible tubulin binding agent that selectively targets the endothelial cells that make up the blood vessel walls in solid tumors. The Company is pursuing the development of a product candidate, OXi4503, which is a dual-mechanism VDA.

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